Tobacco Use and Stomach Cancer in Mizoram
The incidence of stomach cancer in India is lower than that of any other country around the world. But according to a
study published in the Journal, Cancer Epidemiology Biomarkers & Prevention Vol. 14, 1892-1896, August 2005.
In Mizoram, one of the northeastern states of India, a very high age-adjusted incidence of stomach cancer is recorded.
A hospital based case-control study was carried out to identify the influence of tobacco use on the risk of developing
stomach cancer in Mizoram. Among the cases, the risk of stomach cancer was significantly elevated among current
smokers [odds ratio (OR), 2.3; 95% confidence interval (95% CI), 1.4-8.4] but not among ex-smokers. Higher risks were
seen for meiziol (a local cigarette) smokers (OR, 2.2: 95% CI, 1.3-9.3). The increased risk was apparent among
subjects who had smoked for 30 years. The increased risk was significant with 2-fold increase in risk among the
subjects who smoked for 11 pack-years. The risk increased with increasing cumulative dose of tobacco smoked (mg).
Tuibar (tobacco smoke-infused water), used mainly in Mizoram, was seemed to increase the risk of stomach cancer
among current users in both univariate and multivariate models (OR, 2.1; 95% CI, 1.3-3.1). Tobacco chewer alone (OR,
2.6; 95% CI, 1.1-4.2) showed significant risk. Tobacco use in any form [smoking and smokeless (tuibur and chewing)]
increased the risk of stomach cancer in Mizoram independently after adjusting for confounding variables.
study published in the Journal, Cancer Epidemiology Biomarkers & Prevention Vol. 14, 1892-1896, August 2005.
In Mizoram, one of the northeastern states of India, a very high age-adjusted incidence of stomach cancer is recorded.
A hospital based case-control study was carried out to identify the influence of tobacco use on the risk of developing
stomach cancer in Mizoram. Among the cases, the risk of stomach cancer was significantly elevated among current
smokers [odds ratio (OR), 2.3; 95% confidence interval (95% CI), 1.4-8.4] but not among ex-smokers. Higher risks were
seen for meiziol (a local cigarette) smokers (OR, 2.2: 95% CI, 1.3-9.3). The increased risk was apparent among
subjects who had smoked for 30 years. The increased risk was significant with 2-fold increase in risk among the
subjects who smoked for 11 pack-years. The risk increased with increasing cumulative dose of tobacco smoked (mg).
Tuibar (tobacco smoke-infused water), used mainly in Mizoram, was seemed to increase the risk of stomach cancer
among current users in both univariate and multivariate models (OR, 2.1; 95% CI, 1.3-3.1). Tobacco chewer alone (OR,
2.6; 95% CI, 1.1-4.2) showed significant risk. Tobacco use in any form [smoking and smokeless (tuibur and chewing)]
increased the risk of stomach cancer in Mizoram independently after adjusting for confounding variables.
No comments:
Post a Comment